Topic vocabularies

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Keywords or topics are important in identifying studies and / or data objects of interest to users. The MDR emphasises the collection of keywords about studies, because data objects generated by those studies will tend to share the same keywords. Topics can also be listed for data objects, however, when those objects are relatively independent of the study – most obviously for a journal article.

In many cases the keywords or topics will be generated by the data object creators, and in that sense are free text. In others object creators or repositories are constrained to use particular controlled terminologies. In those cases it is useful to identify the terminology system used, as well as the term’s code within it, as it can make searching and filtering easier.

The controlled terminology systems in the MDR system are as follows.

id name description and / or url source
11 Generated by authors Free text, not intentionally part of any controlled vocabulary ECRIN
12 ICD 10 https://icd.who.int/browse10/2016/en ECRIN
13 ICD 11 https://icd.who.int/browse11/l-m/en ECRIN
14 MESH https://www.nlm.nih.gov/mesh/meshhome.html ECRIN
15 SnoMed CT http://www.snomed.org/ ECRIN
16 MedDRA https://www.meddra.org/ ECRIN
17 NCI thesaurus https://ncit.nci.nih.gov/ncitbrowser/ ECRIN
18 Cochrane PICO terminology https://linkeddata.cochrane.org/pico-ontology ECRIN
19 CDISC controlled terminology https://www.cdisc.org/standards/terminology ECRIN
20 LOINC https://loinc.org/ ECRIN
21 ATC drug classification https://www.whocc.no/atc/structure_and_principles/ ECRIN
22 WHO Drug https://www.who-umc.org/whodrug/whodrug-portfolio/ ECRIN
23 IUPAC chemical names and biochemical names. https://iupac.org/what-we-do/nomenclature/ ECRIN
24 InChI chemical identifier https://iupac.org/who-we-are/divisions/division-details/inchi/ ECRIN
25 Enzyme Commission numbers / names https://www.qmul.ac.uk/sbcs/iubmb/ ECRIN
26 HGNC human genome codes / names and related proteins. https://www.genenames.org/ ECRIN
27 Taxonomic names e.g. Linnaean binominals. http://www.iczn.org/iczn/index.jsp ECRIN
0 Not yet known Dummy value supplied by default on entity creation. ECRIN